I do not think some/much/most/all of humanity is setting out to totally eliminate particular non-human species as the Nazis tried to do to the Jews and the Hutus to the Tusis.
Except for the smallpox virus, I don't think Humanity has ever tried to deliberately kill off all of a particular species of life at one go.
So no sins of plenticidal commission here.
But Humanity has always been perfectly willing to turn people out of their homes in dead of winter while burning their villages, bedding, and food stores, killing their animals and poisoning their wells.